Milestone for Nanoelectronics

Juni 16, 2009

In collaboration with the University of Regensburg, Germany, and Utrecht University, Netherlands, IBM scientists demonstrated the ability to measure the charge state of individual atoms using noncontact atomic force microscopy. They imaged and identified differently charged individual gold and silver atoms by measuring the tiny differences in the forces between the tip of an atomic force microscope and a charged or uncharged atom located in close proximity below it. This opens up new possibilities in the exploration of nanoscale structures and devices at the ultimate atomic and molecular limits. These results hold potential to impact a variety of fields such as molecular electronics, catalysis or photovoltaics.
www.ibm.com/us/en/


Molecular Light Switches for Higher Resolution

Mai 29, 2009

The “Superresolution” research network, founded by the German Ministry of Education and Sciences, demonstrated a new widefield microscopy technology with resolutions better than 20 nanometers. The method is based on special dyes, which’s fluorescence can be optically and reversibly switched on and off in aqueous solutions. The dyes are bond to cellular structures by using a functional group. By switching the dyes on and off, the fluorescence emission is separated in time until only those dye molecules fluoresce that have enough distance to allow their localization as single molecules. After several thousand switching cycles, a total image is constructed (dSTORM – direct stochastic optical reconstruction microscopy). Involved in the project were the work groups of Prof. Dr. M. Sauer and Prof. Dr. J. Mattay (University of Bielefeld, Germany ), Prof. Dr. K.-H. Drexhage (University of Siegen, Germany), Prof. Dr. J. Enderlein (University of Goettingen, Germany), and Prof. Dr. S. Hell (Max Planck Institute of Biophysical Chemistry, Goettingen, Germany).
www.biophotonik.org

Cytoskeleton of a fixed cell. Left: Fluorescence image at standard conditions. Right: dSTORM image using molecular switches.

Cytoskeleton of a fixed cell. Left: Fluorescence image at standard conditions. Right: dSTORM image using molecular switches.


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